1.Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

1.结论早期诊断并及时给予别嘌呤醇及利尿是治疗TLS的关键。

2.If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

2.如出现药毒性，其他选择包括其他黄嘌呤抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。