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Despite advances in the diagnosis and treatment of the antineutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitides, renal morbidity is common.

虽然对于抗中性粒浆抗(ANCA)相关性血管诊断和治疗有进展,但是肾脏损害依然很严重。

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Osmosis-肌骨

But unlike many other autoimmune conditions, no autoantibody has been specifically linked to the disease.

他的自免疫不同,至今尚未发现和该特异性相关的自

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Osmosis-泌尿

One way these complexes can form is as a result of autoantibodies directly targeting the glomerular basement membrane.

这些复合物形成的途径之一是自直接攻击肾小球基膜。

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Osmosis-泌尿

The rest of cases, though, are secondary, and seem to arise from autoantibodies that are generated in response to another process like an infection, malignancies, autoimmune conditions, or medications.

另一是继发性的,自来源于对他疾的应答,如感染,恶性肿瘤,自免疫状态或药物等。

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Osmosis-肌骨

For reasons that aren’t completely understood, some autoantibodies that target receptors in the brain have been implicated as well, and this can cause neurologic disorders like seizures and psychosis.

理尚不完全清楚,部分自也会攻击大脑中的受,这会导致神经系统紊乱,如癫痫和精神

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Osmosis-肌骨

Spondyloarthropathies are all autoimmune diseases that affect the joints, and they’re seronegative, which refers to the fact that rheumatoid factor, which is an autoantibody, is not found in the blood.

脊柱关节是一类累及关节、且血清学呈阴性的自免疫;血清学阴性是指患者血液中未发现类风湿子这

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Osmosis-神经

In very rare cases, myasthenia gravis can present as a paraneoplastic syndrome, which means that an underlying cancer like bronchogenic carcinoma or thymic neoplasm (also known as thymoma) generates an immune response which results in generation of autoantibodies.

在极罕见的情况下,重症肌无力会表现出副肿瘤综合征,这意味着潜在的癌症如支气管肺癌、胸腺肿瘤导致免疫应答产生了自

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