In this study, MDS is adopted to simulate the structures of two kinds of metalloprotein, one is Metallothionein (MT), and the other is Cytochrome P450 (CYP).
It is found in the enzyme cytochrome c oxidase, which is part of the respiratory electron-transport chain, and in the protein plastocyanin, which is involved in photosynthetic electron transport.
Many of the drugs used in angina pectoris are the substrate of cytochrome P450, drug interactions are easily to occur when antianginal drugs co-administrated with other drugs and foods.
Some classic examples of these triggers include excessive alcohol consumption, starvation and certain medications that increase cytochrome p450 protein.
In addition, iron is also an important part of proteins like myoglobin, which delivers and stores oxygen in muscles; and mitochondrial enzymes like cytochrome oxidase, which help generate ATP.