Now, among malignant tumors, the most common one is osteosarcoma.

那么，在恶性肿瘤中，最常见的是肉瘤。

Yeah. These are, um...these are x-rays of a human with an osteosarcoma on his tibia.

是啊。看这个...这个X光片显示这个上有成肉瘤。

Osteosarcomas often form in the metaphysis where there’s a lot of cell division occurring.

肉瘤常形成于干骺，为大量细胞分裂。

I just wanted to ask you if you knew the success rate of curing osteosarcoma in a canine leg.

我只想问问如果要治疗它腿上的成肉瘤，成功的机率有多大？

Osteosarcomas arise from osteoblasts of different sizes - called pleomorphic - and these cells produce too much osteoid tissue.

肉瘤起源于大小不同的成细胞（多形性）；这些细胞会产生过多的类组织。

Osteosarcoma form lytic bone lesions, referred to as a sunburst appearance, because the radiating tumor streaks look like sun rays.

肉瘤形成溶性病变，称为“日光放射征”，因为放射状肿瘤状似太阳射线。

Osteosarcoma is linked to RB1 and TP53 genes mutations, while Ewing sarcoma is thought to arise when there are EWSR1, and FLI1 genes mutation.

肉瘤与RB1和TP53基因突变有关，尤因肉瘤被认为源于EWSR1和FLI1基因的易位。