Cases of porencephaly and global atrophyof the temporal lobe were highly related to prenatal or perinatal insults including preterm delivery and asphyxia.

而在洞脑症及颞叶萎缩病童似乎与前或周因素，如早及窒息有。

It is associated with high perinatal mortality, thick fissured skin, marked ectropion (eyelid eersion), eclabium (eersion of the lips), and flexion deformities.

伴有围高死亡率、皮肤肥厚、显著眼睑外翻、唇外翻和节弯曲畸形。