Because ELN mutations cause vascular disease but not cognitive abnormalities, these data implicate LIMK1 hemizygosity in imparied visuospatial constructive cognition.
Ascites has been reported after kidney transplantation due to rejection, decapsulation of the graft, urinary or vascular leak, lymphocele, transudation, or infection.
Now, regardless of type, Kaposi’s sarcoma is an endothelial cell neoplasm, so it causes vascular proliferation, resulting in dark or violaceous plaques.
Finally, endothelial injury increases vascular permeability, allowing water to slip out of blood vessels between neighboring endothelial cells and get into the tissues.
And this has the effect of increasing pulmonary vascular resistance, and to maintain pulmonary blood flow, the body responds by developing pulmonary hypertension.
What’s important though is that since the fetus doesn’t use their lungs yet, there’s relatively high vascular resistance and therefore high pressure in the pulmonary circulation.