There are two important chemicals found in all our brains - dopamine and acetylcholine.

多巴胺和。

It works by blocking the release of a neurotransmitter called acetylcholine, which controls muscle contractions.

的释。正是神经控制肌肉收缩的那道指令。

That's why we prefer the more slow-burn feeling we get when our brains release acetylcholine.

这也是为什么我们比较喜欢脑中释时平稳和缓的感受。

In both cases, the parasympathetic nerve fibers in the cavernosal spaces release acetylcholine from their nerve endings.

在这两种情况下，副交感神经纤维在海绵体间隙通过神经末梢释。

The acetylcholine bind to muscarinic receptors on endothelial cells, which activates the enzyme nitric oxide synthase.

与内皮细胞上的毒受体结合，激活一氧化氮合酶。

Binding of acetylcholine to its receptor activates a chain reaction in the muscle cell that ultimately results in muscle contraction.

ACh与其受体结合激活了肌肉细胞的连锁反应，最终导致肌肉收缩。

Damaged parasympathetic nerve fibers can’t release acetylcholine, so there’s less nitric oxide synthase activation, and less nitric oxide is produced.

受损的副交感神经纤维不能释，因此被激活的一氧化氮合酶较少，产生的一氧化氮也较少。

These neurons use such neurotransmitters as acetylcholine, dopamine, serotonin and others.

这些神经元使用、多巴胺、5-羟色胺等神经递质。

Spinal motor neurons, which synapse on muscle cells, use acetylcholine as their neurotransmitter.

脊髓运动神经元利用作为神经递质作用于肌肉细胞。

Most neurons in the cerebral cortex are called cholinergic neurons, because they produce acetylcholine.

大脑皮层中的大多数神经元为能神经元，因为它们产生作为神经递质。

It's possible that this is because helper T cells, which originate in the thymus, help B cells make antibodies to the acetylcholine receptor.

这可能是因为起源于胸腺的T细胞，帮助B细胞产生ACh受体抗体。

Alright, so in this case, the patient’s B cells inappropriately make antibodies that bind to nicotinic acetylcholine receptors on the muscle cells.

好了，在这种情况下，患者的B细胞产生了错误的抗体，该抗体和肌肉细胞中N受体相结合。

Even though this might be oversimplifying things a bit, the brain regions affected by HD have decreased GABA and acetylcholine, and increased dopamine levels.

尽管这可能有点过于简单化，但罹患HD患者的大脑内GABA和的水平减少，多巴胺水平增高。

The activation of complement causes inflammation and destruction of the muscle cells and reduces the amount of acetylcholine receptors on the surface.

补体激活引起炎症反应，破坏肌肉细胞，减少其表面的受体数量。

The upper motor neuron releases acetylcholine from its axon terminal knobs and these are received by nicotinic receptors on the alpha motor neuron.

上运动神经元从轴突末端释，作用于α运动神经元上的烟受体。

Myasthenia gravis is a type II hypersensitivity disorder where the body produces antibodies that most commonly target nicotinic acetylcholine receptors on the surface of muscle cells.

重症肌无力是一种II型超敏反应，身体产生抗体，常见靶点为肌肉细胞表面的N受体抗体。

Since usually there’s this balance of signaling between dopamine and acetylcholine, a loss of dopamine reaching the striatum increases the relative amount of acetylcholine signalling there.

由于多巴胺和之间有一种平衡，多巴胺减少的信号传到纹状体，导致信号发出相应增加。

Once acetylcholine receptors are bound by the antibody, they are unable to bind to acetylcholine, and therefore don’t respond to the “contract” signal from the central nervous system.

一旦Ach受体与抗体结合，就无法与ACh结合，因此对中枢神经系统的“收缩”信号没有反应。

First you’ve got your motor neurons that release the neurotransmitter acetylcholine at the neuromuscular junction, which then binds to nicotinic acetylcholine receptors on muscle cell membranes.

首先，你的运动神经元在神经肌肉接头处释神经递质（ACh），然后与肌肉细胞膜上的N受体相结合。

Once nicotine is absorbed into the bloodstream, it binds to a type of acetylcholine receptor, called a nicotinic acetylcholine receptor - also called a nicotinic receptor - which is found throughout the body and brain.

一旦尼古丁进入血液循环，它就会和一种受体结合，也称烟型受体或烟受体；这类受体广泛分布于身体和大脑中。