1.This paper reports the improvement on the synthesis of 5 methylisoxazol 3 formamide by Claisen condensation of diethyl oxalacetate followed by cyclization and ammonolysis.

1.讨论了以草酸二乙酯为原料,莱森缩、环、氨成5甲基异唑3甲酰胺工艺的改进。