Ankylosing spondylitis, also called Bechterew disease, is part of a group of diseases called seronegative spondyloarthropathies.

强直炎也称Bechterew病，旧称为“血清阴关节病”的疾病中的种。

Inflammation and pain from ankylosing spondylitis is usually treated with non-steroidal anti-inflammatory drugs like ibuprofen.

强直炎的炎症和疼痛通常采用如布洛芬等非甾体抗炎药来治疗。

Ankylosing spondylitis is a systemic inflammatory disease, so it can cause symptoms, like weight loss, fevers, and fatigue.

强直炎种身的炎症疾病，因此能够引起身症状，如体重减轻、发热和疲劳。

In ankylosing spondylitis there's chronic inflammation of the intervertebral joints and the facet joints of the spine.

患有强直炎时，椎间盘和关节突关节内存在炎症。

All right, as a quick recap, ankylosing spondylitis is an autoimmune process, associated with the HLA-B27 gene, which attacks vertebral joints.

好，简单回顾下：强直炎种与HLA-B27基因有关的自身免疫疾病，会导致关节受累。

Most individuals with ankylosing spondylitis have the gene HLA-B27, which is a gene that encodes for a specific type of MHC class I molecule.

许多强直炎患者都携带HLA-B27基因，该基因能编码种特定的MHC Ⅰ分子。

Ankylosing spondylitis can be diagnosed using MRI, where there's typically erosion and narrowing of the joint spaces early on, and joint fusion later on.

利用MRI可诊断强直炎，病程早期通常可见关节腔的侵蚀和狭窄，晚期可见关节融合。

So ankylosing spondylitis is a chronic inflammatory disease that affects the vertebral joints and makes the spine really stiff, but can also cause inflammation in other parts of the body like the eyes and blood vessels.

因此，强直炎种累及关节并使变得僵直的慢炎症疾病；它也会累及身体其他部位，如眼部和血管。

It can be congenital, meaning that the person is born with it, or acquired, usually due to degenerative disorders like ankylosing spondylitis, where the bones remodel causing intervertebral discs ossification, and the narrowing of the spinal canal.

它可能先天的，也就说患者出生便有这种情况；或获得的，通常原因退行疾病，如强直炎，导致骨重塑，引起椎间盘骨化，进而造成椎管狭窄。