It indicates that a correct mass relation of a meson nonet (especially for the non ideal-mixing meson nonet) should incorporate the effect of the flavor-dependent quarkonia annihilation.
This is the epoch, when the only remaining energy in our universe, is generated due to the decay of protons and the annihilation of individual particles.
To present an opposing political idea, to suggest we wanted something different to eat, to be frank about our tiredness or anxiety, could threaten us with annihilation.