Mismatches between myocardial fatty acid uptake and utilization lead to the accumulation of cardiotoxic lipid species,and cause lipotoxic cardiomyopathy.
游离脂肪酸的摄入和利用的失协调中脂质积聚并进而起脂毒性病。
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Later symptoms include needing a wheelchair because of severe weakness, developing respiratory failure because of a weak diaphragm, scoliosis, and developing dilated cardiomyopathy and arrhythmias since the dystrophin protein is also expressed in heart muscle.
后期症状包括,由于严重的肌无力需坐轮椅,由于膈肌无力会发生呼吸衰竭、脊柱侧凸,因为抗肌萎缩蛋白也表达于心肌纤维,还会引发扩张型心肌病和心律失常。