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The expression of interleukin-5 (IL-5) has been correlated with the maturation and differentiation of eosinophils, and is considered to be a cytokine responsible for allergic inflammation.

IL-5与嗜酸性的成熟和分化密相关, 是过敏性炎过程中的关键因子。

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Osmosis-解剖与生理

Now, in comparison to neutrophils, eosinophils and basophils are far less common.

比起中性粒,嗜酸性粒、嗜碱性粒不常见得多。

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Osmosis-泌尿

This inflammation is caused by infiltration of immune cells, like neutrophils and eosinophils, which then cause inflammation.

这种炎症是由于免疫渗入导致的,比如中性粒嗜酸性粒,从而造成炎症。

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Osmosis-

IL-5, on the other hand, activates eosinophils which promote an immune response by releasing more cytokines and leukotrienes.

另一方面,IL-5激活嗜酸性粒,通过释放更多的因子白三烯来促进免疫反应。

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Osmosis-

The mucus may also contain Charcot-Leyden crystals which are shaped like needles and are formed by the breakdown of eosinophils.

黏液中也可能含有一些针状的Charcot-Leyden晶体,由嗜酸性粒分解形成。

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豪斯医生一

That wouldn't give you an elevated eosinophil count.

脉管炎不会导致嗜酸性粒增加。

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Osmosis-泌尿

Early symptoms include oliguria and eosinophiluria, which is eosinophils in the urine, but also general symptoms like a fever and a rash.

早期症状包括少尿嗜酸性尿,即尿液中存在嗜酸性粒,但也有发烧等一般症状。

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Osmosis-心血管

Loffler syndrome, where eosinophils accumulate in the lung tissue, can also affect the heart tissue, called Loeffler endocarditis or sometimes loeffler endomyocarditis.

嗜酸性粒聚集在肺组织中,也可以累及心脏组织,这种情况叫做Loeffler心内膜炎,有时也叫Loeffler心内膜肌炎。

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Osmosis-心血管

In this case, eosinophils accumulate in the endocardial layer of the heart tissue, causing inflammation and endocardial fibrosis, making it stiffer and again less compliant.

在这类病例中,嗜酸性粒聚集在心脏组织的心内膜层,导致炎症心内膜纤维化,让其更加僵硬、顺应性更差。

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2017级专外有声

Eosinophils take up a red acidic dye called eosin; their main function is to detoxify foreign proteins, especially those causing allergic reactions.

嗜酸性粒吸收一种叫做伊红的红色酸性染料;它们的主功能是解除外源蛋白质,特别是那些引起过敏反应的蛋白质的毒性。

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2017级专外有声

There are five different types of leukocytes: three types of granulocytes (eosinophil, basophil, and neutrophil) and two types of agranulocytes (monocyte and lymphocyte).

三种粒(嗜酸性粒,嗜碱性粒中性粒两种无粒(单核淋巴)。

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Osmosis-解剖与生理

Eosinophils are also phagocytic, and they’re best known for fighting large and unwieldy parasites because eosinophils are much larger than neutrophils and have receptors that are specific for parasites.

嗜酸性粒同样具有吞噬作用,它们以对抗巨大而笨重的寄生虫而闻名,因为嗜酸性粒比中性粒大得多而且有专门针对寄生虫的受体。

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Osmosis-解剖与生理

They stain blue with the dye hematoxylin, and like eosinophils they can be helpful at combating large parasites but also cause inflammation in asthma and allergy responses.

它们用苏木素染色后呈蓝色;像嗜酸性粒一样,它们可以助力奋战寄生虫,但也会引起哮喘过敏反应。

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Osmosis-解剖与生理

Those cytokines start the inflammatory process by making blood vessels leaky and attracting nearby eosinophils, basophils, and mast cells, which release their own cytokines and granules amplifying the inflammation.

通过使血管渗漏并吸引附近的嗜酸性粒、嗜碱性粒肥大;这些集结的释放各自的因子颗粒,放大炎症反应。

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