Results A 13389G deletion in exon 6 was characterized in propositus, and this mutation led to frameshift.
结果先证者表现为酶基外显613389G失,引起移码突变。
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By comparison, most genes have only about 10 exons and are 50 thousand base pairs in length.
相对来说,大多数基因只有10外显子和50kbp长。
Most of these gene mutations are deletions or duplications of one or more exons, and a small amount are point mutations.
基因大多数或多外显子的缺或重复,小部分是点。
Alright, so the dystrophin gene is a huge gene on the X-chromosome, that has 79 exons and is over 2 million base pairs in length.
抗萎缩蛋白基因是X染色体上庞大的基因,含有79外显子,全长超过2000kbp(书上通常缩写bp,碱基对)。
More base pairs and more exons mean that there are more chances for mistakes during meiosis, which is when the egg or sperm are being created.
更多的碱基对和外显子意味着减数分裂时有更多出错的可能,导致生成X染色体上有错误编码序列的卵细胞或者精子。
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