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So in fibrotic livers you can find cannabinoid receptors that have both anti- and pro-fibrogenic effects.

因此在发生纤维既有抗纤维作用也有促纤维作用。

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Osmosis-消

How do these bands of fibrotic tissue form though?

那么这些纤束又是如何形成呢?

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Osmosis-消

As this fibrotic tissue builds up, it starts to compress the central veins and sinusoids.

堆积在一起组织会挤压中央静脉和血窦。

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Osmosis-消

Most commonly, this happens because of hepatic cirrhosis, which is when the liver tissue is replaced by fibrotic functionless tissue.

它大多数由引起,即脏组织被无功能组织替代。

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Osmosis-解剖与生理

If fertilization doesn't happen, then the corpus luteum stops making hormones after around 10 days, becomes fibrotic, and is called the corpus albicans.

如果次级卵母细胞没有受精,大概10天之后,黄体就会停释放激素而纤,形成白体。

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Osmosis-生殖

If fertilization doesn't happen, then the corpus luteum stops making hormones after approximately 10 days, becomes fibrotic, and is called the corpus albicans.

如果未受精,黄体会在大概10天后停生成激素,并纤变成白体。

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Osmosis-消

Also with cirrhotic liver tissue, you'll see that in between these clumps of cells or nodules, is fibrotic tissue and collagen.

在纤脏组织里,成堆细胞或结节之间,还有纤组织和胶原存在。

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Osmosis-消

Alright, as a quick recap, cirrhosis is when inflammation and liver damage causes the liver to become fibrotic and develop scar tissue.

得!快速总结一下:是指由炎症和脏损伤导致脏纤,并形成瘢痕组织。

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Osmosis-消

As part of the subsequent healing process pancreatic stellate cells lay down fibrotic tissue which causes narrowing, or stenosis of the ducts, as well as acinar cell atrophy.

作为后续修复愈合过程一部分,胰腺星状细胞会产生纤组织,造成导管狭窄及腺泡细胞萎缩。

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Osmosis-消

If we zoom out a bit and look at it with the naked eye, we'll again see these nodules, which have fibrotic protein bands in between.

如果我们直接通过肉眼直接观察脏,我们仍会看到这些结节以及填充在他们之间蛋白质束。

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Osmosis-消

The fibrotic tissue, pressure buildup, and diversion of blood from the hepatic circulation essentially reduces the number of functional sinusoidal veins, and the number of functional portal triads in general.

组织形成、门静脉高压和循环血液分流,最终导致了可用血窦静脉数量减少,以及整体上可用门脉三联管数量减少。

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Osmosis-肌骨

In the short term, there is muscle regeneration resulting in muscle fibers of different sizes, but in the long term, the muscles atrophy and are infiltrated by fat and fibrotic tissue, which leaves them really weak.

短期内,肌肉再生造成大小参差肌纤细胞,但是长期下去,肌肉萎缩并且脂肪组织和结缔纤组织增生渗入其间,导致肌肉无力。

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