Finally, if all four alpha genes are deleted, it results in Hb Bart’s hydrops fetalis.

最后，如果存在4个α基因异常，将会导致Hb Bart胎儿水肿。

Severe hypoxia leads to high-output cardiac failure and massive hepatosplenomegaly, resulting in edema all over the body, called hydrops fetalis.

重度缺氧会引起高输出性心力衰竭和巨大肝、脾，进而出现全身性水肿，称为水肿胎儿。

When diagnosed prenatally, Hb Bart’s hydrops fetalis can be treated with intrauterine transfusions and later followed up with bone marrow transplantation.

如果在产，Hb Bart水肿胎儿可通过宫内输血治疗，随后进行骨髓移植。