OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.
Taking the example of the homoaromaticity of cyclooctriene cation and imidazole and oxazole basicity,the essay discusses the application of resonance theory.
In this paper, the new chelating resin (PSIM) with a polythioether backbone bearing imidazole group is first synthesized by the reaction between polychloromethylthiirane and imidazole.