This special genetic process is called imprinting, where only one copy of the gene gets expressed, not both.

这特殊的遗传学过程称为“印记”，印记因的存在使得两个等位因中的个表达个不表达。

Sometimes that methylation occurs on the paternal chromosome even when there’s no imprinting center defect, and that’s called an epimutation.

有时即使印记中心没有突变，父源染色体也可以发生甲，这过程称为表观突变。

Translocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.

SNRNP因易位会破坏核内核糖核蛋白（SNRPN），并将核RNA因移出印记中心，导致这些因的甲沉默。

Alright, as a quick recap, Prader-Willi syndrome is an imprinting disorder, where mutations on only the paternal copy of a chromosome causes the disease.

好，快速回顾下：普拉德-威利综合征是种印记病，仅在父源染色体突变时发生。

If the paternal imprinting center is mutated, the region gets methylated and those genes get turned off, meaning that both the maternal and paternal genes are silenced.

如果父源印记中心突变，因将被甲沉默，导致母源和父源因都处于沉默状态。

A third way to get Prader-Willi syndrome, is a mutation in the imprinting center, which is a sequence of DNA near the Prader-Willi genes that directs imprinting via sex-specific methylation.

第三种导致普拉德-威利综合征的原因是印记中心的突变；印记中心是临近普拉德-威利因的DNA序列，通过性别特异的甲介导印记。

With my " W" Blog, I'm imprinting proper etiquette and fashion sense as well as my philanthropic mandate on a whole new generation much like you did.

在我的" W" 博客里 我正在以全新的姿态写些礼仪规范 时尚资讯以及我的慈善事业 就如您所做的样。