8.Risk factors for leptospirosis include some professions, like people who work in rice-paddies, sugarcane plantations, or people who swim or wade in waters contaminated by animal urines.
9.We were working on pan-coronavirus vaccines, sickle cell anemia gene therapy, malaria with people across the U.S. and in Africa, leptospirosis with people in southeast Asia, vaccines for peanut allergies.
10.For example, Leptospira interrogans, the most common cause of leptospirosis, has adhesins, which are proteins that help this bacteria attach to the host's cells - usually epithelium, monocytes, and macrophages.
11.So Leptospira is a genus of spiral bacteria known to cause leptospirosis, a zoonotic infection, meaning it can be transmitted from animals such as rodents, to humans; especially people who work in sewers and waters contaminated by these animals' urine.