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Novel oncogene with kinase-domain (NOK) can activate multiple mitogenic signaling pathways including the janus kinases (JAK) and signal transducer and activator of transcription proteins (STAT).

NOK能激活包含JAK-STAT信号通路在内的多种促细胞有丝分裂信号通路。

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Neutrophil gelatinase-associated lipocalin(NGAL) is a novel member of the lipocalin family and may be a new human oncogene, but the regulation mechanism of NGAL was not clear in the cancer.

NGAL(neutrophil gelatinase-associated lipocalin)是lipocalin家族的一个新成员,可能是人类的一种新癌基因,但其在的表达调控机制尚不清楚。

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Osmosis-肌骨

So oncogenes or mutated tumor suppressor genes allow cells to keep growing uncontrollably resulting into tumors.

此,或突变的抑使细胞不受控制地增长,导致肿瘤发生。

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Osmosis-内分泌

Oncogenes help cells grow and proliferate, while tumor suppressor genes slow down cell growth and proliferation.

加速细胞生长增殖,而抑使细胞生长增殖变慢。

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Osmosis-解剖与生理

Fusobacteria is another genus of bacteria in the mouth that produces excessive immune responses and activates oncogenes.

梭杆菌属是口腔中另一种会引发过度免疫应答、激活的细菌。

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Osmosis-消

When proto-oncogenes, like epidermal growth factor receptor and RAS, are activated, it turns them into oncogenes that promote cell division.

当原皮生长子受体、RAS)被激活时,它们就变成了促进细胞分裂的

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VOA Standard 2014年6月合集

One new treatment relies on a test to identify damaged genes called oncogenes that allow cancer cells to grow and spread.

一种新疗法是识别出名为致的破损,这种能使得细胞发展和蔓延。

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VOA Standard 2014年6月合集

The results showed that patients whose driver oncogenes were specifically targeted lived, on average, a year longer than those who received standard chemotherapy.

结果显示其致子得到针对性地治疗的患者存活了,平均来说他们比那些接受标准疗的患者多活一年。

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2017级专外有声

Abnormal cell division can occur either when active oncogenes are expressed or when tumor suppressor genes are lost.

当活性达或肿瘤抑制丢失时,可发生异常细胞分裂。

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VOA Standard 2014年6月合集

Oncologist Mark Kris from Memorial Sloan Kettering Cancer Center led a study that examined the role oncogenes play in the spread of cancer.

史隆凯特林症中心的肿瘤专家马克·克里斯负责了一项检验致症蔓延中所起作用的研究。

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Osmosis-生殖

It usually involves several genetic mutations in endometrial cells, including of PTEN, a tumor suppressor gene; PIK3CA, an oncogene; and ARID1A, a gene regulating chromatin structure.

它通常涉及子宫内膜细胞的几种突变,包括抑PTEN、原PIK3CA,及调控染色质结构的ARID1A。

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2017级专外有声

The result is that the cell receives a constant message to divide. This dominant " gain of function gene" is often called an oncogene.

结果是细胞接收一个恒定的消息进行不断分裂。这种显性的" 获得功能" 通常被称为

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Osmosis-内分泌

So both an MYCN amplification or ALK gene fusion, where the oncogene is “turned on, ” or a PHOX2B and chromosome 1 and 11 deletions, where tumor suppressor genes are “turned off, ” can potentially cause uncontrolled cell growth.

此,MYCN扩增或ALK的融合,即致被激活,或PHOX2B与1号、11号染色体缺失,即抑的失活,都可能导致细胞生长不受控制。

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