Other benign tumors are osteoblastomas and osteoid osteomas, both of which arise from osteoblasts.

其他良性肿瘤包括成骨瘤、骨样骨瘤，两者均起源于成骨。

Osteosarcomas arise from osteoblasts of different sizes - called pleomorphic - and these cells produce too much osteoid tissue.

骨肉瘤起源于大小不同的成骨（多形性）；些会产生过多的类骨组织。

Osteoclasts break down the unneeded mineral lattice using acids and enzymes so that osteoblasts can then add more material.

破骨酸和酵素酶 将用的矿物晶格样就可提供 更多原料给造骨。

This means that osteoblasts don't have enough calcium and phosphate to deposit into the organic matrix.

意味着成骨没有足够的钙和磷可沉积到骨有机质中。

These collagen fibers are the framework for the osteoblasts' work.

些胶原纤维为成骨的工作构建了框架。

Now, for bones to grow and develop properly, special bone cells, called osteoblasts, are hard at work.

在骨正常的生长发育过程中，有一种特殊的骨，成骨，起了至关重要的作用。

To build bone, osteoblasts secrete osteoid, which is an organic matrix made of type 1 collagen.

在构建骨的过程中，成骨分泌类骨质，它是一种由1型胶原组成的有机质。

Eventually osteoblasts get activated and a process called ossification will start, which is when the fibrous tissue turns to bone.

最后成骨活化，骨化过程启动，纤维组织最终转化为骨组织。

Bone mineralization is dependent on an enzyme called alkaline phosphatase - which increases in response to osteoblast activity.

骨的矿化依赖碱性磷酸酶；碱性磷酸酶响应成骨活性而增加。

Ok, now, when osteoclasts break down bone faster than the osteoblasts can rebuild it, it results in the lowering of the bone mass and eventually in osteoporosis.

那么，当破骨分骨骼的速度比造骨重建骨骼更快时，骨量就会减少，最终导致骨质疏松。

With senile osteoporosis, on the other hand, it’s believed that osteoblasts just gradually lose the ability to form bone, while the osteoclasts keep doing their thing unabated.

另一方面，老年性骨质疏松被认为是由于造骨逐渐失去造骨的能力，同时破骨持续工作，活力不减。