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Osmosis-

Finally, there are some rare stones made of xanthine, which, just like uric acid, is a byproduct of purine breakdown.

最后,还有黄嘌形成罕见结石,同酸一样,是嘌分解副产物。

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Osmosis-

Since uric acid is a breakdown product of purines, a very common reason for high levels of uric acid is consuming lots of purines.

酸是嘌分解产物,故高酸是大量摄入嘌结果。

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Osmosis-肌骨

To understand where the uric acid comes from, let’s start with purines, which, together with pyrimidines, are nature’s most common nitrogen-containing heterocycles.

为了说明酸从何而来,让我们先来了解嘌啶,它们都是自然界中最常见含氮杂环。

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Osmosis-肌骨

Xanthine oxidase is an enzyme involved in the breakdown of purines to uric acid, so inhibiting this enzyme results in less uric acid production.

黄嘌氧化酶负责分解嘌酸,所以抑制这个酶,就可以减少生成。

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Osmosis-肌骨

These crystals can form as a result of increased consumption of purines, like from consuming purine-rich foods like shellfish, anchovies, red meat or organ meat.

这种结晶成因有嘌摄入过多,如摄入富含嘌食物,像是贝壳、沙丁鱼、红肉或动物内脏。

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Osmosis-肌骨

Also, though, they can result from increased production of purines, for example high-fructose corn syrup containing beverages could contribute to the formation of uric acid by increasing purine synthesis.

但同时,这也可能是于嘌生成过多,如高果糖饮食、玉米糖浆饮料会促进嘌合成,从而生成酸。

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