Methods The sciatic and brachial plexus nerve of three-day-old SD mice was treated with collagenase type IV and trypsin to remove the desmocyte on the Schwann cell, then explanted in the culture disk.
The sciatic nerve then passes beneath the piriformis muscle, and through the greater sciatic foramen, which is an opening formed by the pelvic bone, sacrospinous and sacrotuberous ligaments.
Since the pain is associated with injury or compression of the sciatic nerve, and follows the path of the sciatic nerve, it makes sense to name it sciatica.