Since usually there’s this balance of signaling between dopamine and acetylcholine, a loss of dopamine reaching the striatum increases the relative amount of acetylcholine signalling there.

由于多巴胺和乙之间有一种平衡，多巴胺减少的信号传到纹状体，导致乙信号发出相应增加。

But interestingly, if those offered a reward the first time are asked to participate again for no reward, scans show a decrease in activity in the anterior striatum and prefrontal areas，parts of the brain linked to self-motivation.

但有趣的是，如果那第一次得到奖赏的被试在第二次必须无偿参与任务，他们的外侧纹状体和前额区域活会降低，这部分脑区与励相关。

Over time, if enough of the neurons die in the caudate and putamen, which together form the dorsal striatum, then it can cause actual loss of brain tissue volume in that area and expansion of the lateral ventricles.

随着时间的推移，如果由尾状核和壳核构成的背侧纹状体内死亡的神经元细胞越来越多，会引起该区域的脑组织减少，进而导致侧脑室扩大。