carcinogenesis

Abstract: Pyrrolizidine alkaloids(PAs) are widely distributed in plantae.Many PAs are hepatotoxic,Lung toxicity(carcinogenesis),neurotoxic and cytotoxic.

摘 要： 吡咯里西啶生物碱广泛分物界。

Results With the progress of oral carcinogenesis, regular changes of epithelial cell were showed: decrease in tonofibril, keratohyaline granules, desmosome;

结果随大鼠舌癌变进展，鳞状上皮细胞浆、核、细胞间连接、基底膜等发生规律性变。

In the fields of epigenetics and epigenomics, DNA methylation has been drawn a special attention because of its close correlation to human development and carcinogenesis.

DNA甲基已经成为表观遗传学和表观基因组学重要研究内容，人类表观基因组计划目标是绘制出人类基因组中甲基可变位点图谱。