cyano

Two series of tolan-type liquid crystals containing terminal cyano group were synthesized.

设计并合成了一类新型末端氰基取代含氟二苯乙炔类液晶。

cyano 4’ methyl phenylbenzene, a key intermediate of Sartan drug, was synthesized from 4 bromotoluene and 2 bromobenzonitrile in the present of cuprous bromide as a catalyst. The yield is 50%.

以溴化亚铜为催化剂,将邻苯甲腈与溴甲苯偶制备了合成沙坦类药物的关键中间体2氰基4′甲基苯,收率50%。