2.OBJECTIVE:RP HPLC method for the determination of content of 5 hydroxymethyl furfuraldehyde(5 HMF) in mitoxantrone dextrose injections is reported.
目:采用HPLC测定盐酸醌葡萄糖注射中5羟甲基糠醛。
3.Methods:Chloroform being solvent,under bath heat,4 hydroxymethyl caged bicyclic phosphate acylated with pentanoyl chloride and hexanoyl chloride dividedly.
方法:用氯仿作溶剂,在浴温条件下,4羟甲基笼状双环磷酸酯分别与戊酰氯、己酰氯发生酰化反应。
4.Two kinds of products can be obtained in the addition reaction of benzaldoxime with propinol, in which 3-hydroxymethyl-dihydroisoxazol is the main product when reaction equilibrium is reached.