allopurinol

1.If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

出现药物毒性，其他选择包括其他黄嘌呤氧酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

2.Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉尿是治疗TLS的关键。