1.The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.
组蛋白酰化和去酰化由一对功能抗的蛋白酶——组蛋白酰转移酶和组蛋白去酰化酶负责。
2.Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.