bioactivation

Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.

近来，有研究表明线粒体乙醛脱是体内硝酸甘油生物主要途径，线粒体乙醛脱同时具有脱和酯活性，其酯活性可以通过将硝酸甘油脱硝形成一氧氮，进而血管扩张。