1.Conclusion Intrathecal escin and clonidine alone produced a dose-dependent treatment effects on neuropathic pain.The synergistic effect was found between intrathecal escin and clonidine.
结论大鼠鞘内单独注射七皂苷钠或可乐定可产生剂量依赖性抗神经病理性疼痛作用;
2.Clonidine and neostigmine are α2 adrenergic receptor agonist and acetycholine esterase catastaltic, Animal experiment and clinical research confirmed that both of them have analgesic effect.
3.Methods HPLC method was utilized to determine the ingredients which were individually extracted from clonidine hydrochloride, hydrochlorothiazide, rutin and linarin of flos chrysanthemi indici.